Meta-analysis of the effects of exercise intervention on glucose metabolism and body composition in patients with type 2 diabetes mellitus - Takeaways - MDSpire

Meta-analysis of the effects of exercise intervention on glucose metabolism and body composition in patients with type 2 diabetes mellitus

  • By

  • Yuqing Liu

  • Mingyuan Zhao

  • Baoshan Qian

  • June 29, 2026

  • 0 min

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  • 1

    Exercise intervention significantly reduced glycated hemoglobin in patients with type 2 diabetes mellitus (T2DM) with a standardized mean difference of -0.46.

  • 2

    Combined exercise produced greater improvements in glycemic control compared to aerobic exercise alone, with a standardized mean difference of -0.71.

  • 3

    Exercise intervention significantly reduced fasting blood glucose levels in patients with T2DM, achieving a standardized mean difference of -0.52.

  • 4

    Exercise intervention resulted in a significant reduction in BMI and improved maximal oxygen uptake (VO2max) in patients with T2DM.

  • 5

    The study included 16 randomized controlled trials with a total of 1401 samples, evaluated using the Cochrane Risk of Bias Assessment Tool.

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