Risk factors for thrombosis in tuberculosis patients admitted to a tuberculosis-dedicated intensive care unit: a retrospective cohort study - Takeaways - MDSpire

Risk factors for thrombosis in tuberculosis patients admitted to a tuberculosis-dedicated intensive care unit: a retrospective cohort study

  • By

  • Aifeng Liu

  • Yuewen Qiu

  • Hongmei Chen

  • Xiaohua Ma

  • June 30, 2026

  • 0 min

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  • 1

    Advanced age and prolonged activated partial thromboplastin time (APTT) are independent predictors of thrombus formation in tuberculosis patients.

  • 2

    Fungal co-infection significantly increases thrombotic risk, while non-TB bacterial co-infection appears to have a protective effect.

  • 3

    The study included 168 tuberculosis patients in the ICU, with 101 diagnosed with thrombosis and 67 without.

  • 4

    The addition of inflammatory biomarkers CRP, D-dimer, or IL-6 did not significantly improve the predictive model for thrombosis.

  • 5

    C-reactive protein (CRP) is independently associated with IL-6 levels, serving as a reliable surrogate marker in this population.

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