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1
Heparin-induced thrombocytopenia (HIT) can complicate heparin therapy, leading to severe thrombotic events despite therapeutic dosing.
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2
Unexplained heparin resistance, even before thrombocytopenia, may indicate HIT and necessitates immediate diagnostic evaluation.
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3
In a case study, a 50-year-old man with acute pulmonary embolism exhibited heparin resistance and recurrent thrombosis prior to HIT diagnosis.
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4
Switching from heparin to non-heparin anticoagulants, like argatroban, is crucial for managing suspected HIT to prevent life-threatening complications.
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5
Follow-up revealed significant thrombus resolution and normalized cardiac function after appropriate management of HIT.
