Rapid progression of recurrent intracranial solitary fibrous tumor following a previously reported TERT-wild-type primary tumor: a case report - Takeaways - MDSpire
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Accelerated Recurrence of Intracranial Solitary Fibrous Tumor After TERT-Wild-Type Primary Tumor: A Case Study

  • By

  • Longfei Shao

  • Chao Yang

  • Xukun Teng

  • Jianmin Yang

  • Jinyang Li

  • Yinghao Gu

  • Shuo Sun

  • September 8, 2026

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  • 1

    Intracranial solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm, constituting approximately 0.09% of intracranial tumors.

  • 2

    The case study details a 70-year-old male with recurrent SFT after a TERT-wild-type primary tumor, showing rapid clinical deterioration.

  • 3

    The recurrent tumor exhibited a Ki-67 index of 70%, indicating significant proliferative activity compared to the primary tumor's 15%.

  • 4

    Differential diagnosis between dura-based SFTs and meningiomas is critical due to overlapping imaging characteristics and differing management.

  • 5

    The original histology slides from the primary tumor were unavailable, limiting independent verification of its WHO grade and characteristics.

Original Source(s)

Rapid progression of recurrent intracranial solitary fibrous tumor following a previously reported TERT-wild-type primary tumor: a case report

  • by Longfei Shao, Chao Yang, Xukun Teng, Jianmin Yang, Jinyang Li, Yinghao Gu, Shuo Sun

  • September 8, 2026

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