The Usefulness of White Blood Cell Inflammatory Parameters in Children With Systemic Lupus Erythematosus - Takeaways - MDSpire
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Clinical Value of White Blood Cell–Based Inflammatory Markers in Children With Systemic Lupus Erythematosus

  • By

  • Butsabong Lerkvaleekul

  • Nongnuch Sirachainan

  • Duantida Songdej

  • Karan Paisooksantivatana

  • Pawadee Chinudomwong

  • Soamarat Vilaiyuk

  • October 13, 2026

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  • 1

    Childhood-onset SLE is often more severe than adult-onset disease, making accurate assessment of disease activity important.

  • 2

    White blood cell inflammatory parameters use fluorescence flow cytometry signals from routine CBC testing to characterize immune cell activation and morphology.

  • 3

    The study examined associations between WBC-IP and disease activity in children with SLE and compared their performance with conventional inflammatory markers.

  • 4

    The prospective cohort enrolled patients younger than 18 years at Ramathibodi Hospital from May 2021 through March 2023.

  • 5

    Disease activity was measured with SLEDAI-2K, and inactive disease was defined as a clinical SLEDAI-2K score of 0 regardless of treatment.

Original Source(s)

The Usefulness of White Blood Cell Inflammatory Parameters in Children With Systemic Lupus Erythematosus

  • by Butsabong Lerkvaleekul, Nongnuch Sirachainan, Duantida Songdej, Karan Paisooksantivatana, Pawadee Chinudomwong, Soamarat Vilaiyuk

  • October 13, 2026

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