Depressive symptom patterns in older adults: evidence from two national ageing cohorts

1

The study identified four reproducible depressive symptom patterns in older adults: Minimal Symptoms, Somatic-Motivational, Affective-Social, and Global Distress.
2

Latent class analysis revealed strong cross-cohort structural correspondence for the identified symptom patterns in both the HRS and ELSA cohorts.
3

The Somatic-Motivational pattern was associated with higher odds of future elevated depressive symptoms and increased risk of ADL worsening and mortality.
4

Adding symptom patterns to traditional CES-D total scores improved model fit and identified risks beyond what was expected from score-based assessments.
5

The findings support the use of symptom configuration as a complementary approach to late-life risk assessment in depressive disorders.

Frontiers In Psychiatry

1