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1
An 8-week standardized Qingpao Chushi Jiedu Fang (QCF) treatment significantly improved clinical severity in palmoplantar pustulosis (PPP) patients.
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2
Clinical assessments showed significant reductions in PPPASI and DLQI scores after QCF treatment, indicating improved quality of life.
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3
Oral microbial diversity and community structure changed significantly post-treatment, with smokers showing more pronounced effects.
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4
Cytokine levels, including IL-1β, IL-4, and IFN-α, decreased, while IFN-γ increased, suggesting a modulation of inflammatory responses.
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5
The study highlights potential microbiome-immune interactions in PPP, warranting further investigation into TCM's effects on oral microbiota.
