Dietary background, serum polyunsaturated fatty acid profiles, and 1-year outcomes after large-artery atherosclerotic stroke: a multicenter cohort study - Takeaways - MDSpire

Dietary background, serum polyunsaturated fatty acid profiles, and 1-year outcomes after large-artery atherosclerotic stroke: a multicenter cohort study

  • By

  • Xiaoci Lin

  • Zhihao Zhao

  • Daijun Zhu

  • Guogu Shen

  • Xuri Xu

  • Yinyan Li

  • July 10, 2026

  • 0 min

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  • 1

    The study enrolled 410 patients with large-artery atherosclerotic cerebral infarction for a one-year follow-up assessment.

  • 2

    Patients were divided into high-fish/seafood and mixed/omnivorous dietary groups based on their long-term dietary habits.

  • 3

    At one-year follow-up, the high-fish/seafood group showed better neurological outcomes and lower rates of post-stroke depression.

  • 4

    Serum PUFA analysis revealed higher ω-3 levels and lower ω-6/ω-3 ratios in the high-fish/seafood group.

  • 5

    Higher ω-6/ω-3 ratios correlated with poorer functional outcomes and increased risks of post-stroke depression and cognitive impairment.

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