Accuracy of frameless stereotactic brain biopsy: a retrospective cohort study with MRI-only and MRI-CT fusion navigation - Takeaways - MDSpire

Accuracy of frameless stereotactic brain biopsy: a retrospective cohort study with MRI-only and MRI-CT fusion navigation

  • By

  • Franziska Meinert

  • Patrick Dömer

  • Simeon O. A. Helgers

  • Levent Tanrikulu

  • Johannes Woitzik

  • Nikhil Wendt-Thakur

  • December 20, 2025

  • 0 min

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  • 1

    Frameless stereotactic biopsy is essential for histopathological confirmation of unclear intracranial lesions when resection is not indicated.

  • 2

    The VarioGuide® system offers a minimally invasive alternative to frame-based techniques, reducing operative time and morbidity.

  • 3

    MRI-only navigation may face geometric distortions, while MRI-CT fusion navigation can enhance accuracy in frameless biopsies.

  • 4

    This study analyzed 99 patients who underwent frameless stereotactic biopsy, comparing MRI-only and MRI-CT fusion navigation techniques.

  • 5

    Postoperative CT scans were used to assess accuracy, measuring entry point deviation from the planned trajectory in biopsies.

Original Source(s)

Accuracy of frameless stereotactic brain biopsy: a retrospective cohort study with MRI-only and MRI-CT fusion navigation

  • by Franziska Meinert, Patrick Dömer, Simeon O. A. Helgers, Levent Tanrikulu, Johannes Woitzik, Nikhil Wendt-Thakur

  • December 20, 2025

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