Gut microbiota and metabolomic characteristics associated with metabolic syndrome in post-cholecystectomy patients: a retrospective cross-sectional study - Takeaways - MDSpire

Gut microbiota and metabolomic characteristics associated with metabolic syndrome in post-cholecystectomy patients: a retrospective cross-sectional study

  • By

  • Yue Lou

  • Xiangping Wang

  • June 22, 2026

  • 0 min

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  • 1

    Cholecystectomy patients with metabolic syndrome exhibited reduced microbial richness and altered gut microbiota composition.

  • 2

    The metabolic syndrome group showed a lower Firmicutes/Bacteroidetes ratio and increased Prevotella abundance.

  • 3

    Metabolomic analysis indicated elevated secondary bile acids and decreased short-chain fatty acids, particularly butyrate, in metabolic syndrome patients.

  • 4

    Correlation analysis linked gut microbiota changes to inflammatory markers and adverse metabolic indices in post-cholecystectomy patients.

  • 5

    The study suggests further investigation into dietary modulation and microbiota-targeted strategies for post-cholecystectomy patients with metabolic syndrome.

Original Source(s)

Gut microbiota and metabolomic characteristics associated with metabolic syndrome in post-cholecystectomy patients: a retrospective cross-sectional study

  • by Yue Lou, Xiangping Wang

  • June 22, 2026

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