Shorter DAPT Tested Following CABG

TOP-CABG compared 3 months vs 12 months of ticagrelor plus aspirin following bypass surgery.

1

Three months of ticagrelor-based dual antiplatelet therapy was noninferior to 12 months for saphenous vein graft occlusion after CABG.
2

The shorter DAPT duration significantly reduced clinically relevant bleeding compared to the longer duration in selected CABG patients.
3

The trial included 2,300 patients, with a mean age of 61.5 years, and assessed outcomes at 1 year post-surgery.
4

Major adverse cardiovascular events were similar between the 3-month and 12-month DAPT groups, but the trial was not powered for these differences.
5

Findings may not apply to all antiplatelet regimens or patients with specific conditions, limiting generalizability of the results.

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