Shorter DAPT Tested Following CABG - Takeaways - MDSpire
Coming Soon: Introducing MDSpire News. Learn more
Conexiant’s news site is now MDSpire News. Learn more

Shorter DAPT Tested Following CABG

TOP-CABG compared 3 months vs 12 months of ticagrelor plus aspirin following bypass surgery.

  • By

  • Kathryn Wighton

  • June 8, 2026

  • 6 min

Share

  • 1

    Three months of ticagrelor-based dual antiplatelet therapy was noninferior to 12 months for saphenous vein graft occlusion after CABG.

  • 2

    The shorter DAPT duration significantly reduced clinically relevant bleeding compared to the longer duration in selected CABG patients.

  • 3

    The trial included 2,300 patients, with a mean age of 61.5 years, and assessed outcomes at 1 year post-surgery.

  • 4

    Major adverse cardiovascular events were similar between the 3-month and 12-month DAPT groups, but the trial was not powered for these differences.

  • 5

    Findings may not apply to all antiplatelet regimens or patients with specific conditions, limiting generalizability of the results.

Original Source(s)

Shorter DAPT Tested Following CABG

  • by Kathryn Wighton

  • June 8, 2026

Related Content

Aortic Dissection at 25: Recognizing a Life-Threatening Emergency in a Young Athlete

An aortic dissection occurs when a tear develops in the inner layer of the aorta, the body’s largest artery. Blood can force its way between layers of the vessel wall, compromising circulation to vital organs or causing catastrophic internal bleeding.

  • by

  • September 22, 2026

  • 7 min
Frailty may not limit semaglutide benefits

Patients with greater frailty showed larger improvements in health-related quality of life, while cardiovascular treatment effects did not differ significantly across frailty categories.

Tricuspid regurgitation thresholds reassessed

The proposed framework classified 30% of patients as high or extreme risk, compared with 12% classified as having severe or greater tricuspid regurgitation under established grading schemes.