Platelet to high-density lipoprotein cholesterol ratio predicts clinical outcomes after acute ischemic stroke: a prospective cohort study - Takeaways - MDSpire

Platelet to high-density lipoprotein cholesterol ratio predicts clinical outcomes after acute ischemic stroke: a prospective cohort study

  • By

  • Xuan Sun

  • Haochen Sun

  • Zhijia Tang

  • Xinyang Qi

  • Xian Wang

  • Xiaoyin Wang

  • June 30, 2026

  • 0 min

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  • 1

    The study included 820 patients with acute ischemic stroke, assessing the platelet/high-density lipoprotein cholesterol ratio (PHR) as a prognostic marker.

  • 2

    Higher PHR levels were associated with increased risks of all-cause death and stroke recurrence at 3 months, 6 months, and 1 year.

  • 3

    Kaplan–Meier survival curves indicated that patients in the highest PHR tertile had the worst clinical outcomes.

  • 4

    Subgroup analysis revealed significant interactions between PHR and age for all-cause death, and BMI for poor functional outcomes.

  • 5

    The addition of PHR to a basic model improved its predictive ability for clinical outcomes in patients with acute ischemic stroke.

Original Source(s)

Platelet to high-density lipoprotein cholesterol ratio predicts clinical outcomes after acute ischemic stroke: a prospective cohort study

  • by Xuan Sun, Haochen Sun, Zhijia Tang, Xinyang Qi, Xian Wang, Xiaoyin Wang

  • June 30, 2026

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