Updated Estimates of Agreement Between Dispensed Medications and Forensic Toxicology in Sweden - Takeaways - MDSpire
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Revised Assessments of Correlation Between Prescribed Medications and Forensic Toxicology Findings in Sweden

  • By

  • Heidi Taipale

  • Jari Tiihonen

  • Antti Tanskanen

  • Jonas Forsman

  • September 24, 2026

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  • 1

    The study updated the assessment of medication exposure using the PRE2DUP method, focusing on forensic toxicology findings in Sweden.

  • 2

    Revisions excluded observations from periods with inconsistent testing, resulting in analyses of 10,060 individuals for affected substances.

  • 3

    Predicted adherence and Cohen's κ showed significant improvements for several drug classes, particularly cardiovascular medications.

  • 4

    Antidepressants like duloxetine and paroxetine also demonstrated increased predicted adherence and Cohen's κ after dataset refinement.

  • 5

    The study emphasizes the importance of consistent testing methods for accurate modeling of drug exposure in forensic toxicology.

Original Source(s)

Updated Estimates of Agreement Between Dispensed Medications and Forensic Toxicology in Sweden

  • by Heidi Taipale, Jari Tiihonen, Antti Tanskanen, Jonas Forsman

  • September 24, 2026

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