Clinically significant tumor histology in suspected primary bladder cancer: is every transurethral resection necessary? - Takeaways - MDSpire

Clinically significant tumor histology in suspected primary bladder cancer: is every transurethral resection necessary?

  • By

  • Conrad Leitsmann

  • Alexander Stephan Reese

  • Richard Zigeuner

  • Hanna Zurl

  • Klara Pohl

  • Johannes Mischinger

  • Iva Simunovic

  • Carl Ketterer

  • Florestan Koll

  • Sebastian Mannweiler

  • Marianne Leitsmann

  • Sascha Ahyai

  • June 12, 2026

  • 0 min

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  • 1

    Transurethral resection of bladder tumor (TURBT) is the standard diagnostic and treatment approach for non-muscle-invasive bladder cancer (NMIBC).

  • 2

    In a study of 217 patients, 35% were found to have no malignancy after TURBT, indicating potential overuse of the procedure.

  • 3

    Significant predictors of malignancy included papillary findings, age, interobserver congruence, and tumor size.

  • 4

    Interobserver congruence on preoperative and TURBT findings was observed in 80.6% of cases, highlighting diagnostic reliability.

  • 5

    The study suggests that TURBT may not be necessary for all patients with suspected bladder lesions, advocating for more selective criteria.

Original Source(s)

Clinically significant tumor histology in suspected primary bladder cancer: is every transurethral resection necessary?

  • by Conrad Leitsmann, Alexander Stephan Reese, Richard Zigeuner, Hanna Zurl, Klara Pohl, Johannes Mischinger, Iva Simunovic, Carl Ketterer, Florestan Koll, Sebastian Mannweiler, Marianne Leitsmann, Sascha Ahyai

  • June 12, 2026

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