Right ventricular–pulmonary arterial uncoupling and venous excess in normotensive pulmonary embolism shock - Takeaways - MDSpire
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Uncoupling of Right Ventricular and Pulmonary Arterial Function with Venous Overload in Normotensive Shock Due to Pulmonary Embolism

  • By

  • José Carlos Gasca-Aldama

  • Karen Harumi López-Rodríguez

  • Mario Arturo Carrasco-Flores

  • Juan Ángel Morales-Ferrer

  • Osvaldo Alexis Marché-Fernández

  • Marcos Vidals-Sánchez

  • José Ernesto Juárez-León

  • Mónica Libertad Moya-Alfaro

  • Eduardo Alberto González-Escudero

  • September 3, 2026

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  • 1

    The article discusses the identification of normotensive shock in acute pulmonary embolism using a multi-parametric diagnostic framework.

  • 2

    A reduced TAPSE/PASP ratio is independently associated with 30-day mortality in patients with acute pulmonary embolism.

  • 3

    The Venous Excess Ultrasound Score (VExUS) correlates with disease severity in acute pulmonary embolism and aids in risk stratification.

  • 4

    Inadequate tricuspid regurgitation velocity (TRV) limits the use of TAPSE/PASP, necessitating alternative metrics for assessing right ventricular function.

  • 5

    A VExUS score > 1 shows excellent diagnostic accuracy for identifying high-risk pulmonary embolism, with high sensitivity and specificity.

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