A patient with triple-negative breast cancer developed acute myocardial infarction after docetaxel chemotherapy: case report and literature review - Takeaways - MDSpire

A patient with triple-negative breast cancer developed acute myocardial infarction after docetaxel chemotherapy: case report and literature review

  • By

  • Fangqin Tong

  • Zhipeng Fan

  • Huiling Huang

  • Chen Chen

  • Jingzhou Xiang

  • Na Li

  • Min Xia

  • Lei Li

  • May 29, 2026

  • 0 min

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  • 1

    Docetaxel treatment in a patient with triple-negative breast cancer led to an acute ST-segment elevation myocardial infarction.

  • 2

    Coronary angiography revealed severe occlusions in multiple coronary arteries, necessitating timely percutaneous coronary intervention.

  • 3

    Docetaxel is associated with fewer reports of cardiotoxicity compared to paclitaxel, but can still cause severe adverse reactions.

  • 4

    The patient had no prior cardiovascular risk factors, highlighting the underestimated cardiotoxic potential of docetaxel.

  • 5

    A comprehensive review of 94 cases from the FAERS database was conducted to analyze taxane-associated myocardial infarction.

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