Comparative accuracy of spectral computed tomography and conventional computed tomography in colorectal cancer staging

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Spectral CT demonstrated higher overall TNM accuracy for colorectal cancer staging compared to conventional CT, with rates of 74.2% versus 63.0%.
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The study included 340 adults with pathologically confirmed colorectal cancer, comparing spectral CT (151 patients) and conventional CT (189 patients).
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Spectral CT showed superior accuracy in T-stage (74.2% vs 57.7%) and N-stage (74.8% vs 64.0%) assessments, while M-stage accuracy was comparable.
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Agreement with the reference standard was higher for spectral CT, with weighted kappa values of 0.815 for overall TNM compared to 0.795 for conventional CT.
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The findings suggest that spectral CT may improve pre-treatment staging accuracy in colorectal cancer, enhancing treatment planning and risk stratification.

Frontiers In Oncology

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