Case report: Non-surgical triumph in pericardial paraganglioma: durable tumor regression via targeted embolization of coronary collaterals - Takeaways - MDSpire

Case report: Non-surgical triumph in pericardial paraganglioma: durable tumor regression via targeted embolization of coronary collaterals

  • By

  • Zaiqiang Zhang

  • Jiawang Ding

  • May 11, 2026

  • 0 min

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  • 1

    Pericardial tumors are rare cardiovascular disorders, with an incidence of 0.001% to 0.007% and account for 6.7% to 12.8% of primary cardiac tumors.

  • 2

    A 60-year-old woman with a pericardial paraganglioma underwent transcatheter embolization of a circumflex artery fistula, leading to significant tumor regression.

  • 3

    Multimodal imaging, including CT and MRI, was essential for diagnosing the pericardial tumor and planning its non-surgical management.

  • 4

    Post-embolization, the patient's urinary catecholamine levels normalized, and she reported substantial resolution of symptoms at the one-year follow-up.

  • 5

    This case demonstrates the potential of targeted embolization as a non-surgical treatment option for inoperable pericardial paragangliomas.

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