Dynamic changes in serum albumin, prealbumin, and retinol-binding protein after head and neck cancer surgery: a retrospective cohort study

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The study analyzed serum albumin, prealbumin, and retinol-binding protein levels in 200 head and neck cancer patients before and after surgery.
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Patients were divided into a control group receiving conventional nutritional support and an intervention group receiving intensive nutritional intervention.
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One week post-surgery, the intervention group had significantly higher levels of albumin, prealbumin, and retinol-binding protein compared to the control group.
4

The intervention group also exhibited lower inflammatory markers and shorter time to first oral intake and hospital stay.
5

Prealbumin and retinol-binding protein were found to be more sensitive indicators for assessing perioperative nutritional status than albumin.

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