Transdiagnostic Internet-delivered intervention for children and adolescents with anxiety and depressive disorders: a randomized controlled trial

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Internalizing problems, including anxiety and depression, are prevalent in youth, with significant long-term consequences if untreated.
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Access to mental health services for youth is severely limited, particularly in low-resource countries like Romania.
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Internet-delivered interventions have shown promise in reducing anxiety symptoms among youth, though results for depression are mixed.
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Rational Emotive Behavioral Therapy (REBT) is effective for treating anxiety and depression and is suitable for transdiagnostic interventions.
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The REBTonAd intervention consists of nine modules targeting core mechanisms of anxiety and depression, enhancing scalability for youth mental health care.

Npj Digital Medicine

by Anca Dobrean, Costina-Ruxandra Poetar, Ionuț-Stelian Florean, Raluca Balan, Gerhard Andersson
January 16, 2026

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