Evaluation of Donor Vessel Using Quantitative Flow Ratio in Patients with Chronic Total Occlusions - Takeaways - MDSpire

Evaluation of Donor Vessel Using Quantitative Flow Ratio in Patients with Chronic Total Occlusions

  • By

  • Xinjian Li

  • Juntao Duan

  • Lin Mi

  • Liyuan Tao

  • Xinye Xu

  • Guisong Wang

  • March 12, 2026

  • 0 min

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  • 1

    Coronary chronic total occlusions (CTO) affect about 25% of patients with obstructive coronary artery disease, often leading to collateral circulation.

  • 2

    Quantitative flow ratio (QFR) is an effective method for assessing coronary artery function without requiring pressure wires or hyperemia.

  • 3

    Murray law-based QFR (µQFR) simplifies the QFR assessment by using a single angiographic projection, enhancing feasibility in CTO patients.

  • 4

    The study retrospectively analyzed 336 patients with single-vessel CTO to compare µQFR and 3D-QFR for evaluating donor vessel function.

  • 5

    Results indicated the need for further investigation into the agreement between µQFR and 3D-QFR in the context of collateral donor vessels.

Original Source(s)

Evaluation of Donor Vessel Using Quantitative Flow Ratio in Patients with Chronic Total Occlusions

  • by Xinjian Li, Juntao Duan, Lin Mi, Liyuan Tao, Xinye Xu, Guisong Wang

  • March 12, 2026

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