BMP-2 Linked to Bone Consolidation in Revision THA

Small retrospective study found 10-year implant survivorship in severe acetabular defects

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BMP-2 augmentation during revision total hip arthroplasty improved radiographic bone consolidation in patients with severe acetabular defects.
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In a study of 15 patients, 83% of hips showed over 50% bone consolidation at final follow-up after BMP-2 treatment.
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Implant survivorship rates were 90% at 6 years and 70% at 10 years, indicating favorable long-term outcomes.
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Postoperative complications occurred in 28% of hips, with infection and dislocation being the most common issues.
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The study's limitations include its retrospective design, small sample size, and lack of preoperative patient-reported outcomes.

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