Association of preoperative CT-derived visceral adipose tissue index with synchronous metastasis and metastasis-free survival after curative-intent surgery in colorectal cancer - Takeaways - MDSpire

Association of preoperative CT-derived visceral adipose tissue index with synchronous metastasis and metastasis-free survival after curative-intent surgery in colorectal cancer

  • By

  • Ke Yin

  • Yuchen Xie

  • Qingling Li

  • Guanyi Liao

  • Song He

  • Jinjun Guo

  • June 2, 2026

  • 0 min

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  • 1

    Preoperative CT-derived visceral adipose tissue index (VATI) is linked to synchronous metastasis in colorectal cancer (CRC).

  • 2

    Higher VATI is associated with shorter metastasis-free survival (MFS) in patients undergoing curative surgery for non-metastatic CRC.

  • 3

    In multivariable analysis, VATI remained an independent predictor of MFS alongside CA19-9, CEA, N stage, and lymphovascular invasion.

  • 4

    The study included 468 patients, with 77 having metastatic CRC and 391 non-metastatic CRC, analyzed for VATI's impact on metastasis.

  • 5

    VATI may serve as a useful biomarker for risk stratification and postoperative surveillance in CRC, pending further validation.

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