Effects of Chemotherapy on the Development of Lymphedema in Breast Cancer Patients: A Retrospective Analysis - Takeaways - MDSpire

Effects of Chemotherapy on the Development of Lymphedema in Breast Cancer Patients: A Retrospective Analysis

  • By

  • Liqin Wang

  • Yuemin Weng

  • Weiqi Wei

  • Jun Bu

  • Cici Zhang

  • April 27, 2026

  • 0 min

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  • 1

    Chemotherapy was associated with breast cancer-related lymphedema (BCRL) in 15.4% of patients studied.

  • 2

    Taxane-based regimens, long-course chemotherapy, and combined neoadjuvant and adjuvant chemotherapy significantly increased BCRL risk.

  • 3

    Univariate analysis identified tumor stage, axillary lymph node dissection, and regional nodal irradiation as significant BCRL risk factors.

  • 4

    The study included 201 patients who underwent surgical treatment for breast cancer between January 2020 and December 2023.

  • 5

    Findings suggest the need for vigilant monitoring for BCRL in patients receiving specific chemotherapy regimens.

Original Source(s)

Effects of Chemotherapy on the Development of Lymphedema in Breast Cancer Patients: A Retrospective Analysis

  • by Liqin Wang, Yuemin Weng, Weiqi Wei, Jun Bu, Cici Zhang

  • April 27, 2026

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