Hepatitis D Virus Seroconversion Rate Among People With Chronic Hepatitis B Virus Infection in France and The Gambia (Inci-D) - Takeaways - MDSpire

Hepatitis D Virus Seroconversion Rate Among People With Chronic Hepatitis B Virus Infection in France and The Gambia (Inci-D)

  • By

  • Patrick Ingiliz

  • Erwan Vo-Quang

  • Gibril Ndow

  • Maud Lemoine

  • Amie Ceesay

  • Sainabou Drammeh

  • Marie-Noëlle Hilleret

  • Laure Bordy

  • Thomas Decaens

  • Anne-Laure Mazialivoua

  • Yusuke Shimakawa

  • Alhagie B Touray

  • Jean-Michel Pawlotsky

  • Isabelle Chemin

  • Stephane Chevaliez

  • Vincent Leroy

  • December 26, 2025

  • 0 min

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  • 1

    The Inci-D study analyzed HDV superinfection rates in HBsAg-positive individuals from France and The Gambia.

  • 2

    Baseline HDV prevalence was 1.1% in The Gambia and 2.5% in France among the studied cohorts.

  • 3

    After follow-up, new HDV antibody positivity was detected at rates of 3.85/1000 patient-years in The Gambia and 3.70/1000 patient-years in France.

  • 4

    Chronic HBV/HDV infection leads to more severe liver disease progression compared to HBV monoinfection.

  • 5

    The findings support the need for repeated HDV serology testing in HBsAg-positive individuals for better patient management.

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