Prevalence and associated factors of gestational diabetes mellitus among women with polycystic ovary syndrome: a systematic review and meta-analysis - Takeaways - MDSpire

Prevalence and associated factors of gestational diabetes mellitus among women with polycystic ovary syndrome: a systematic review and meta-analysis

  • By

  • Youchang Yuan

  • Liuxin Hu

  • Yanjing Li

  • Xinju Hou

  • July 17, 2026

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  • 1

    Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in reproductive-aged women, significantly increasing the risk of gestational diabetes mellitus (GDM).

  • 2

    The systematic review included 22 studies with 5,507 PCOS patients, revealing a pooled GDM prevalence of 24% with substantial heterogeneity (I² = 89.9%).

  • 3

    GDM prevalence was higher with one-step diagnostic criteria (26.0%) compared to two-step criteria (18.7%) among women with PCOS.

  • 4

    Associated factors for GDM in PCOS patients included pre-pregnancy BMI, gestational weight gain, HOMA-IR, and family history of diabetes.

  • 5

    The findings highlight the need for targeted screening and management strategies for GDM in women with PCOS, based on observed data.

Original Source(s)

Prevalence and associated factors of gestational diabetes mellitus among women with polycystic ovary syndrome: a systematic review and meta-analysis

  • by Youchang Yuan, Liuxin Hu, Yanjing Li, Xinju Hou

  • July 17, 2026

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