Trimodal prehabilitation and psychological outcomes in colorectal cancer surgery: preliminary findings from a single-center randomized trial - Takeaways - MDSpire

Trimodal prehabilitation and psychological outcomes in colorectal cancer surgery: preliminary findings from a single-center randomized trial

  • By

  • Elisa Trevisol

  • Nicolò Fabbri

  • Antonio Pesce

  • Rosario Lordi

  • Maria Giulia Nanni

  • Rosangela Caruso

  • Luigi Grassi

  • Carlo Vittorio Feo

  • July 10, 2026

  • 0 min

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  • 1

    A trimodal prehabilitation program was evaluated for its effects on anxiety and depression in colorectal cancer surgery patients.

  • 2

    The study involved 45 patients, with 20 receiving trimodal prehabilitation and 25 receiving standard ERAS care.

  • 3

    GAD-7 scores significantly decreased in the intervention group, indicating reduced anxiety compared to controls.

  • 4

    No significant differences were found in depressive symptoms (PHQ-9 scores) between the two groups over time.

  • 5

    Improvements in emotional functioning and cancer-related fatigue were noted in the intervention group.

Original Source(s)

Trimodal prehabilitation and psychological outcomes in colorectal cancer surgery: preliminary findings from a single-center randomized trial

  • by Elisa Trevisol, Nicolò Fabbri, Antonio Pesce, Rosario Lordi, Maria Giulia Nanni, Rosangela Caruso, Luigi Grassi, Carlo Vittorio Feo

  • July 10, 2026

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