Cognitive impairment and associated factors in elderly patients with schizophrenia: a retrospective observational study with phenotype analysis - Takeaways - MDSpire

Cognitive impairment and associated factors in elderly patients with schizophrenia: a retrospective observational study with phenotype analysis

  • By

  • Yanping Cai

  • Yinxia Wu

  • Danjing Yao

  • Ying Xu

  • April 30, 2026

  • 0 min

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  • 1

    Cognitive impairment prevalence among elderly patients with schizophrenia is 47.7%, significantly impacting their quality of life.

  • 2

    Higher perceived social support and better activities of daily living scores are associated with lower odds of cognitive impairment.

  • 3

    Diabetes mellitus is linked to increased odds of cognitive impairment in elderly patients with schizophrenia.

  • 4

    K-means clustering identified three cognitive and psychosocial phenotypes, highlighting heterogeneity in this population.

  • 5

    The study emphasizes the need for individualized nursing interventions to improve outcomes for elderly patients with schizophrenia.

Original Source(s)

Cognitive impairment and associated factors in elderly patients with schizophrenia: a retrospective observational study with phenotype analysis

  • by Yanping Cai, Yinxia Wu, Danjing Yao, Ying Xu

  • April 30, 2026

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