Omadacycline for peritoneal dialysis-associated peritonitis caused by Coxiella burnetii: a case report and literature review - Takeaways - MDSpire

Omadacycline for peritoneal dialysis-associated peritonitis caused by Coxiella burnetii: a case report and literature review

  • By

  • Xiaobing Hong

  • Zinan Cai

  • Zelin Yu

  • Hongbo Fu

  • Jianpeng Cai

  • Zhijian Wu

  • Xiuming Wu

  • Zejian Kuang

  • July 14, 2026

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  • 1

    Peritoneal dialysis-associated peritonitis (PDAP) significantly contributes to hospitalization and mortality rates in patients undergoing peritoneal dialysis.

  • 2

    A 62-year-old male with recurrent PDAP unresponsive to standard antibiotics was diagnosed with Coxiella burnetii using metagenomic next-generation sequencing.

  • 3

    The patient was treated with omadacycline, achieving hemodynamic stability and normalization of inflammatory markers within 48 hours.

  • 4

    Despite confounding factors, the patient's clinical recovery suggests omadacycline may be a viable alternative for treating C. burnetii infections.

  • 5

    The case emphasizes the importance of accurate pathogen identification in PDAP to guide effective treatment strategies.

Original Source(s)

Omadacycline for peritoneal dialysis-associated peritonitis caused by Coxiella burnetii: a case report and literature review

  • by Xiaobing Hong, Zinan Cai, Zelin Yu, Hongbo Fu, Jianpeng Cai, Zhijian Wu, Xiuming Wu, Zejian Kuang

  • July 14, 2026

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