Hepatocellular carcinoma risk stratification to identify patients suitable for intensive surveillance in viral hepatitis: the SELECT score - Takeaways - MDSpire

Hepatocellular carcinoma risk stratification to identify patients suitable for intensive surveillance in viral hepatitis: the SELECT score

  • By

  • Yeun-Yoon Kim

  • Won Chang

  • Jeong Min Lee

  • Se Woo Kim

  • Jae Seok Bae

  • Jeongin Yoo

  • Sun Kyung Jeon

  • HeeSoo Kim

  • Young Hoon Kim

  • Jin-Young Choi

  • Eun Ju Cho

  • Yun Bin Lee

  • Sook-Hyang Jeong

  • Do Young Kim

  • Yunhee Choi

  • Jeong Hee Yoon

  • October 25, 2025

  • 0 min

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  • 1

    Hepatocellular carcinoma (HCC) is the leading cause of cancer-related deaths, emphasizing the need for effective surveillance in high-risk patients.

  • 2

    Ultrasound (US) is commonly used for HCC surveillance but has limited sensitivity for early-stage detection, necessitating alternative imaging methods.

  • 3

    The SELECT score was developed to predict HCC risk using US features and clinical data in patients with viral hepatitis eligible for intensive surveillance.

  • 4

    A retrospective study analyzed data from three institutions to validate the SELECT score, focusing on patients aged 40-75 with chronic hepatitis B or C.

  • 5

    The model aims to identify patients with an estimated annual HCC incidence ≥ 2.5%, improving the cost-effectiveness of intensive surveillance.

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