Uveitis and retinal vasculitis associated with varicella-zoster virus: a case study and review of existing literature on vitrectomy management - Takeaways - MDSpire

Uveitis and retinal vasculitis associated with varicella-zoster virus: a case study and review of existing literature on vitrectomy management

  • By

  • Jingjing Tian

  • Yuze Jiang

  • Nannan Ye

  • Yankun Zhang

  • March 9, 2026

  • 0 min

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  • 1

    Varicella-Zoster Virus (VZV) can cause uveitis and retinal vasculitis, particularly affecting patients with weakened immune systems.

  • 2

    The case study highlights a 74-year-old male with VZV-induced uveitis diagnosed through metagenomic next-generation sequencing.

  • 3

    Timely vitrectomy was performed, successfully preserving the patient's vision despite severe ocular complications.

  • 4

    Postoperative treatment included intravitreal ganciclovir and oral valacyclovir, leading to significant improvement in visual acuity.

  • 5

    The study emphasizes the importance of early diagnosis and intervention in preventing blindness from VZV-related ocular complications.

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