Combined metabolic-reproductive association and predictive value of AMH and TyG index in PCOS: a single-center retrospective study - Takeaways - MDSpire

Combined metabolic-reproductive association and predictive value of AMH and TyG index in PCOS: a single-center retrospective study

  • By

  • Yu Chen

  • Xinyan Shi

  • Lin Ma

  • Yujie Hu

  • Mei Wang

  • Lei Shu

  • July 8, 2026

  • 0 min

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  • 1

    The study analyzed 628 participants to investigate the independent and synergistic associations of AMH and the TyG index with PCOS.

  • 2

    AMH and the TyG index were confirmed as independent risk factors for PCOS, with significant interaction identified between them.

  • 3

    In subgroup analyses, a strong positive association between the TyG index and PCOS risk was found in the low AMH subgroup.

  • 4

    A dose-response relationship for PCOS risk was observed across different combinations of AMH and TyG index levels.

  • 5

    The predictive model combining AMH and the TyG index showed the highest accuracy for PCOS risk assessment.

Original Source(s)

Combined metabolic-reproductive association and predictive value of AMH and TyG index in PCOS: a single-center retrospective study

  • by Yu Chen, Xinyan Shi, Lin Ma, Yujie Hu, Mei Wang, Lei Shu

  • July 8, 2026

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