Distinctive vascular changes in the retina and choroid linked to retrograde flow in the ophthalmic artery due to chronic total occlusion of the carotid artery - Takeaways - MDSpire
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Distinctive vascular changes in the retina and choroid linked to retrograde flow in the ophthalmic artery due to chronic total occlusion of the carotid artery

  • By

  • Ling Feng

  • Xiaofeng Tan

  • Le Cao

  • Hang Wang

  • Yueyue He

  • William Robert Kwapong

  • Hong Chen

  • Bo Wu

  • April 20, 2026

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  • 1

    Chronic total occlusion of the internal carotid artery relies on collateral circulation, particularly retrograde flow in the ophthalmic artery.

  • 2

    Retinal vessel length density is significantly lower in eyes with chronic total occlusion compared to those with severe carotid artery stenosis and controls.

  • 3

    Choroidal vascular parameters remain relatively preserved in chronic total occlusion eyes compared to those with severe carotid artery stenosis.

  • 4

    Retrograde ophthalmic artery flow is associated with lower retinal vessel length density but higher choroidal vascular volume and index.

  • 5

    The study highlights distinct vascular changes in the retina and choroid due to hemodynamic alterations from carotid artery occlusion.

Original Source(s)

Distinctive vascular changes in the retina and choroid linked to retrograde flow in the ophthalmic artery due to chronic total occlusion of the carotid artery

  • by Ling Feng, Xiaofeng Tan, Le Cao, Hang Wang, Yueyue He, William Robert Kwapong, Hong Chen, Bo Wu

  • April 20, 2026

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