Late recurrence and histological progression of a cervical intradural extramedullary solitary fibrous tumor after gross total resection: a case report - Takeaways - MDSpire

Late recurrence and histological progression of a cervical intradural extramedullary solitary fibrous tumor after gross total resection: a case report

  • By

  • Yergen N. Kenzhegulov

  • Daniyar K. Zhamoldin

  • Viktor G. Aleinikov

  • Talgat T. Kerimbayev

  • Berik Zhetpisbaev

  • Makar P. Solodovnikov

  • Aisa Z. Nurpeisov

  • Serik Akshulakov

  • June 15, 2026

  • 0 min

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  • 1

    A 39-year-old male developed cervical myelopathy due to a solitary fibrous tumor at the C4–C5 level, requiring microsurgical gross total resection.

  • 2

    Histopathological evaluation revealed a CNS WHO grade 2 solitary fibrous tumor with diffuse CD34 and STAT6 positivity after initial surgery.

  • 3

    Five years post-resection, the patient experienced recurrent cervical pain and sensory disturbances, with MRI showing a localized recurrent lesion.

  • 4

    Histological examination of the recurrent tumor indicated progression to CNS WHO grade 3, characterized by increased mitotic activity and tumor necrosis.

  • 5

    The case underscores the need for long-term radiological follow-up and potential multidisciplinary evaluation for recurrent or higher-grade solitary fibrous tumors.

Original Source(s)

Late recurrence and histological progression of a cervical intradural extramedullary solitary fibrous tumor after gross total resection: a case report

  • by Yergen N. Kenzhegulov, Daniyar K. Zhamoldin, Viktor G. Aleinikov, Talgat T. Kerimbayev, Berik Zhetpisbaev, Makar P. Solodovnikov, Aisa Z. Nurpeisov, Serik Akshulakov

  • June 15, 2026

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