Grading urothelial carcinoma with probe-based confocal laser endomicroscopy during flexible cystoscopy - Takeaways - MDSpire

Grading urothelial carcinoma with probe-based confocal laser endomicroscopy during flexible cystoscopy

  • By

  • Ben-Max de Ruiter

  • Jan Erik Freund

  • C. Dilara Savci-Heijnink

  • Jons W. van Hattum

  • Theo M. de Reijke

  • Joyce Baard

  • Guido M. Kamphuis

  • D. Martijn de Bruin

  • Jorg R. Oddens

  • July 27, 2024

  • 0 min

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  • 1

    Bladder cancer is the 10th most common cancer globally, with urothelial carcinoma accounting for over 90% of cases in high-income countries.

  • 2

    Non-muscle invasive bladder cancer has high recurrence rates, leading to significant patient burden and healthcare costs due to frequent cystoscopic follow-ups.

  • 3

    Probe-based confocal laser endomicroscopy (CLE) offers real-time assessment of suspicious bladder lesions during flexible cystoscopy.

  • 4

    The CystoflexF probe is compatible with flexible cystoscopes and has similar imaging properties to the UroflexF probe, which has shown diagnostic promise.

  • 5

    The CLETUR trial aims to evaluate the diagnostic accuracy of CLE during flexible cystoscopy and compare it with the CystoflexUHD-R probe.

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