Correlation of histologic, imaging, and artificial intelligence features in NAFLD patients, derived from Gd-EOB-DTPA-enhanced MRI: a proof-of-concept study

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NAFLD includes simple steatosis and NASH, with NASH posing higher risks of liver-related morbidity and mortality.
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Current NASH diagnosis relies on invasive liver biopsy, which has limitations including sampling errors and poor patient acceptance.
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Gd-EOB-DTPA-enhanced MRI can differentiate between simple steatosis and NASH using relative liver enhancement and fat fraction measurements.
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A hybrid deep learning approach was tested to identify predictive patterns in MRI that distinguish simple steatosis from NASH.
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The study utilized a derivation and validation cohort to assess the effectiveness of MRI features in diagnosing NASH.

European Radiology

by Nina Bastati, Matthias Perkonigg, Daniel Sobotka, Sarah Poetter-Lang, Romana Fragner, Andrea Beer, Alina Messner, Martin Watzenboeck, Svitlana Pochepnia, Jakob Kittinger, Alexander Herold, Antonia Kristic, Jacqueline C. Hodge, Stefan Traussnig, Michael Trauner, Ahmed Ba-Ssalamah, Georg Langs
June 26, 2023

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