Guselkumab Shows Psoriasis Benefit in Darker Skin Tones

Randomized trial suggests sustained clearance across darker skin tones.

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Guselkumab significantly improved skin clearance in patients with darker skin tones suffering from moderate to severe plaque psoriasis.
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In a trial, 74% of patients receiving guselkumab achieved clear or almost clear skin at week 16, compared to 0% in the placebo group.
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The study showed that 57% of guselkumab-treated patients achieved at least 90% improvement in psoriasis severity by week 16.
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Patient-reported outcomes, including quality of life and itch scores, improved alongside clinical measures in the guselkumab group.
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Adverse events were more common in the guselkumab group, but serious events were rare, indicating a favorable safety profile.

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