Guselkumab Shows Psoriasis Benefit in Darker Skin Tones - Takeaways - MDSpire
From the Journals

Guselkumab Shows Psoriasis Benefit in Darker Skin Tones

Randomized trial suggests sustained clearance across darker skin tones.

  • By

  • Andrea Surnit

  • May 14, 2026

  • 3 min

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  • 1

    Guselkumab improves skin clearance in moderate to severe plaque psoriasis.

  • 2

    74% achieved clear skin (IGA of 0 to 1) at week

  • 3

    103 participants were enrolled in the trial.

  • 4

    Adverse events recorded in 38% of patients, mainly infections.

  • 5

    Most participants had Fitzpatrick skin types IV to VI.

  • 6

    Responses maintained through week 48, showing durability.

  • 7

    Study funded by Johnson & Johnson.

  • 8

    No new safety signals identified through 48 weeks.

Original Source(s)

Guselkumab Shows Psoriasis Benefit in Darker Skin Tones

  • by Andrea Surnit

  • May 14, 2026

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