Development and validation of a simplified pre-screening model for diabetic foot ulcer identification in diabetic patients - Takeaways - MDSpire

Development and validation of a simplified pre-screening model for diabetic foot ulcer identification in diabetic patients

  • By

  • Weidi Wang

  • Yue Guo

  • Sining Chen

  • Wenshi Ou

  • Qiaoyi Wu

  • May 29, 2026

  • 0 min

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  • 1

    A simplified pre-screening tool for diabetic foot ulcers (DFU) was developed using clinical indicators, focusing on the Alb/HbA1c ratio.

  • 2

    The study analyzed 1,854 hospitalized patients and 678 outpatients to identify predictors of DFU using LASSO and logistic regression.

  • 3

    Four independent predictors of DFU were identified: age, history of injury, alcohol consumption, and Alb/HbA1c ratio.

  • 4

    The model demonstrated good discrimination with AUC values of 0.807 in the training set and 0.817 in the validation set.

  • 5

    This pre-screening model aims to rule out DFU in low-probability patients, reducing unnecessary medical consultations.

Original Source(s)

Development and validation of a simplified pre-screening model for diabetic foot ulcer identification in diabetic patients

  • by Weidi Wang, Yue Guo, Sining Chen, Wenshi Ou, Qiaoyi Wu

  • May 29, 2026

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