Cost-Effectiveness of Smoking Cessation Interventions Integrated Into Lung Cancer Screening - Takeaways - MDSpire
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Economic Evaluation of Smoking Cessation Strategies within Lung Cancer Screening Programs

  • By

  • Pianpian Cao

  • Laney Smith

  • Emma Tian

  • Lou-Anne Chichester

  • Elizabeth Schofield

  • Randi M. Williams

  • Rafael Meza

  • Benjamin A. Toll

  • Jamie Ostroff

  • Elena B. Elkin

  • Steven S. Fu

  • Stephanie R. Land

  • Kathryn L. Taylor

  • Jinani Jayasekera

  • September 14, 2026

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  • 1

    Lung cancer is the second most diagnosed cancer in the US, with over 80% of cases linked to cigarette smoking.

  • 2

    The USPSTF expanded LDCT screening eligibility in 2021 to adults aged 50 to 80 years with significant smoking history.

  • 3

    The SCALE Collaboration was established to evaluate the effectiveness of smoking cessation interventions in LDCT screening.

  • 4

    Four randomized clinical trials analyzed 23 intervention arms assessing counseling and pharmacotherapy for smoking cessation.

  • 5

    The study utilized the LuCID-Sim microsimulation model to project long-term health and economic outcomes of cessation strategies.

Original Source(s)

Cost-Effectiveness of Smoking Cessation Interventions Integrated Into Lung Cancer Screening

  • by Pianpian Cao, Laney Smith, Emma Tian, Lou-Anne Chichester, Elizabeth Schofield, Randi M. Williams, Rafael Meza, Benjamin A. Toll, Jamie Ostroff, Elena B. Elkin, Steven S. Fu, Stephanie R. Land, Kathryn L. Taylor, Jinani Jayasekera

  • September 14, 2026

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