Fascia’s role in the mind-body continuum: a novel target for integrative treatments in psychiatry

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Fascia is a connective tissue network that plays a significant role in the pathophysiology of psychiatric disorders like depression and anxiety.
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Fascia facilitates mechanotransduction, proprioception, and nociception, acting as a biological interface between peripheral tissues and the central nervous system.
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Chronic stress can lead to fascial stiffness and inflammation, potentially worsening stress-related psychiatric conditions.
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Preliminary evidence suggests fascial-targeted therapies, such as myofascial release and yoga, may have therapeutic potential in psychiatric treatment.
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Further research is needed to explore the mechanisms of the fascia-psychiatry connection and validate the efficacy of fascial therapies in mental health care.

Frontiers In Psychiatry

by S Mudasser Shah, Muhammad Jahangir, Ghada Saleh Alhudaithi, Chand Taneja, Fatimah Sayer Alharbi, Xiuyun Lin
April 30, 2026

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