COVID Vaccine in Pregnancy: Link to Development?

Multicenter study finds equivalent ASQ-3 scores at 18–30 months in offspring of vaccinated and unvaccinated mothers

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Children born to vaccinated mothers showed equivalent neurodevelopmental outcomes compared to those born to unvaccinated mothers.
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The study involved 271 exposed and 240 unexposed mothers, with matching on key characteristics in 217 pairs.
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The primary outcome showed a median difference of -3.4 points in neurodevelopmental scores, within the prespecified equivalence margin.
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Secondary outcomes indicated no significant differences in various validated assessment tools between the two groups.
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The findings provide reassurance regarding the safety of mRNA SARS-CoV-2 vaccination during pregnancy.

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