Predictive Models for Time to First Opioid Use Disorder or Opioid Overdose Among Older Adults - Takeaways - MDSpire

Forecasting Models for Initial Onset of Opioid Use Disorder or Overdose in the Elderly Population

  • By

  • Chien-Wei Chiang

  • Guy Brock

  • Siegfried Schmidt

  • Roger B. Fillingim

  • Stephan Schmidt

  • Yu-Jung Jenny Wei

  • July 16, 2026

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  • 1

    Opioid use disorder and overdose rates have significantly increased among US adults aged 65 and older from 2000 to 2020.

  • 2

    High-risk opioid use occurs in less than 5% of older adults before the onset of opioid use disorder or overdose.

  • 3

    Current predictive models for opioid use disorder primarily focus on younger populations and may not apply to older adults.

  • 4

    The study utilized Health and Retirement Study data linked with Medicare claims to develop prediction models for older adults.

  • 5

    Key predictors of opioid use disorder or overdose in older adults include patient-reported factors and prescription opioid use.

Original Source(s)

Predictive Models for Time to First Opioid Use Disorder or Opioid Overdose Among Older Adults

  • by Chien-Wei Chiang, Guy Brock, Siegfried Schmidt, Roger B. Fillingim, Stephan Schmidt, Yu-Jung Jenny Wei

  • July 16, 2026

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