A rare and massive retroperitoneal leiomyoma: a case report - Takeaways - MDSpire

A rare and massive retroperitoneal leiomyoma: a case report

  • By

  • Sujuan Jiang

  • Tingting Bai

  • Zhongwen Zou

  • Mengying Wang

  • Wenjing Xu

  • Mengze Xu

  • Kaiting Huang

  • Jie Wang

  • Mingwei Lv

  • Xue Li

  • Xiaoguang Shao

  • Jie Zhang

  • June 1, 2026

  • 0 min

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  • 1

    A 52-year-old woman presented with a giant retroperitoneal leiomyoma, measuring 48×48×25 cm, causing significant symptoms including fever and oliguria.

  • 2

    The surgical procedure involved transabdominal resection, total hysterectomy, and bilateral salpingo-oophorectomy, with innovative techniques for hemodynamic stability.

  • 3

    Postoperative pathology confirmed a spindle cell tumor consistent with degenerative changes of leiomyoma, highlighting the challenges in distinguishing benign from malignant tumors.

  • 4

    The patient's psychological distress was addressed, resulting in a significant reduction in her Hamilton Anxiety Scale score from 21 to 9 postoperatively.

  • 5

    This case underscores the importance of multidisciplinary collaboration and psychological support in managing complex retroperitoneal masses.

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