-
1
Endometriosis (EMS) is a chronic gynecological disease characterized by ectopic tissue growth, pain, and infertility.
-
2
Traditional theories of EMS, such as retrograde menstruation, do not fully explain its complex clinical heterogeneity.
-
3
Imbalances in gut and reproductive microbiomes are increasingly recognized as key factors in the pathogenesis of EMS.
-
4
Ferroptosis, an iron-dependent form of cell death, plays a dual role in EMS by influencing lesion formation and affecting reproductive function.
-
5
The article proposes a framework linking microbiome dysbiosis, iron overload, and ferroptosis to better understand EMS pathogenesis.
