Differential biomarker responses of hemolysis, inflammation, and myocardial injury after pulsed-field pulmonary vein isolation: balloon-in-basket vs. circular catheter systems - Takeaways - MDSpire

Differential biomarker responses of hemolysis, inflammation, and myocardial injury after pulsed-field pulmonary vein isolation: balloon-in-basket vs. circular catheter systems

  • By

  • Jan-Per Wenzel

  • Raed Abdessadok

  • Charlotte Eitel

  • Sorin Popescu

  • Suzanne de Waha

  • Tanja Zeller

  • Karl-Heinz Kuck

  • Roland Richard Tilz

  • Sascha Hatahet

  • May 29, 2026

  • 0 min

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  • 1

    This study compared biomarker changes in hemolysis, inflammation, and myocardial injury between balloon-in-basket and circular catheter PFA systems.

  • 2

    Both PFA systems significantly increased leukocytes, CRP, LDH, troponin, and CK without notable inter-group differences.

  • 3

    Haptoglobin levels decreased significantly in both groups, with a more pronounced decline observed in the PulseSelect group.

  • 4

    Renal function remained stable in most patients, although one patient in the PulseSelect group experienced transient acute kidney injury.

  • 5

    Overall biomarker responses were comparable, but modest system-specific differences warrant further investigation in larger studies.

Original Source(s)

Differential biomarker responses of hemolysis, inflammation, and myocardial injury after pulsed-field pulmonary vein isolation: balloon-in-basket vs. circular catheter systems

  • by Jan-Per Wenzel, Raed Abdessadok, Charlotte Eitel, Sorin Popescu, Suzanne de Waha, Tanja Zeller, Karl-Heinz Kuck, Roland Richard Tilz, Sascha Hatahet

  • May 29, 2026

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