Nafamostat mesilate for anticoagulation in pediatric trauma patients undergoing extracorporeal membrane oxygenation: a two-center observational study in Northwest China - Takeaways - MDSpire

Nafamostat mesilate for anticoagulation in pediatric trauma patients undergoing extracorporeal membrane oxygenation: a two-center observational study in Northwest China

  • By

  • Weikai Wang

  • Zhe Lv

  • Haitong Wu

  • Hua Zhang

  • Zhen Chen

  • Yong Zhou

  • Zhangyan Guo

  • Jingmei Li

  • Le Ma

  • Dan Yao

  • Ying Wang

  • Ru Lin

  • Yajun Niu

  • Yuhao Ma

  • Xinxin Yan

  • Shan Jia

  • Taining Zhang

  • Yufei Wang

  • Yanqiang Du

  • Yi Wang

  • July 14, 2026

Share

  • 1

    Accidental injury is a leading cause of mortality in pediatric patients, often requiring ECMO support due to severe trauma.

  • 2

    This study compares nafamostat mesilate and unfractionated heparin for anticoagulation in pediatric trauma patients on ECMO.

  • 3

    Forty patients were divided into two groups: 24 received nafamostat mesilate and 16 received unfractionated heparin.

  • 4

    The UFH group had a higher incidence of new-onset active bleeding and circuit thrombosis compared to the nafamostat mesilate group.

  • 5

    Nafamostat mesilate provides effective anticoagulation with a significantly lower risk of bleeding than unfractionated heparin.

Original Source(s)

Nafamostat mesilate for anticoagulation in pediatric trauma patients undergoing extracorporeal membrane oxygenation: a two-center observational study in Northwest China

  • by Weikai Wang, Zhe Lv, Haitong Wu, Hua Zhang, Zhen Chen, Yong Zhou, Zhangyan Guo, Jingmei Li, Le Ma, Dan Yao, Ying Wang, Ru Lin, Yajun Niu, Yuhao Ma, Xinxin Yan, Shan Jia, Taining Zhang, Yufei Wang, Yanqiang Du, Yi Wang

  • July 14, 2026

Related Content

Precision medicine directed therapy enabling long-term survival in medulloblastoma: a case report

Long-Term Outcomes and Predictors After Percutaneous Balloon Pulmonary Valvuloplasty for Pediatric Isolated Valvular Pulmonary Stenosis: A Systematic Review

Error in Article Information

  • July 9, 2026