Characteristics of In- and Off-season Respiratory Syncytial Virus Episodes—United States, 2016–2020 - Takeaways - MDSpire

Characteristics of In- and Off-season Respiratory Syncytial Virus Episodes—United States, 2016–2020

  • By

  • Jennifer Judy

  • Kari Yacisin

  • Jessica E Atwell

  • Elizabeth Begier

  • Daniel Curcio

  • Alejandro Cané

  • August 19, 2025

  • 0 min

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  • 1

    The study analyzed RSV episodes in the US from 2017 to 2020, comparing in-season and off-season occurrences.

  • 2

    A total of 141,427 in-season and 3,756 off-season RSV episodes were identified among children, and 41,735 in-season and 1,243 off-season episodes among adults.

  • 3

    Infants constituted the majority of both in-season and off-season pediatric RSV cases, with significant racial disparities noted.

  • 4

    Off-season pediatric episodes had a higher proportion of antibiotic use and were more likely to involve patients with underlying conditions.

  • 5

    The findings highlight the need for enhanced understanding of RSV epidemiology to inform public health interventions.

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