Case Report: Indocyanine green fluorescence imaging in complex focal nodular hyperplasia resection: report of two cases - Takeaways - MDSpire

Case Report: Indocyanine green fluorescence imaging in complex focal nodular hyperplasia resection: report of two cases

  • By

  • Fangkai Du

  • Xie Song

  • Wentao Wang

  • Huizhong Shi

  • Zhengjian Wang

  • Chaoqun Ma

  • Qingqiang Ni

  • Shunzhen Zheng

  • Hong Chang

  • June 15, 2026

  • 0 min

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  • 1

    Indocyanine green (ICG) fluorescence imaging combined with intraoperative ultrasonography (IOUS) aids in laparoscopic excision of focal nodular hyperplasia (FNH).

  • 2

    Two patients with perivascular FNH lesions underwent successful wedge excision using ICG fluorescence, achieving negative surgical margins and minimal blood loss.

  • 3

    Preoperative ICG administration (0.5 mg/kg) allowed real-time fluorescence imaging, enhancing lesion delineation and margin assessment during surgery.

  • 4

    Incidental hyperfluorescent foci were noted on the liver surface; one showed benign changes, while the significance of others remains uncertain.

  • 5

    The report highlights the potential of ICG fluorescence in complex FNH cases, though further studies are necessary to evaluate its broader clinical applicability.

Original Source(s)

Case Report: Indocyanine green fluorescence imaging in complex focal nodular hyperplasia resection: report of two cases

  • by Fangkai Du, Xie Song, Wentao Wang, Huizhong Shi, Zhengjian Wang, Chaoqun Ma, Qingqiang Ni, Shunzhen Zheng, Hong Chang

  • June 15, 2026

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