Peri-interventional antibiotic prophylaxis in endoscopic valve implantation for lung volume reduction in COPD patients: results from a German multicenter observational cohort - Takeaways - MDSpire

Peri-interventional antibiotic prophylaxis in endoscopic valve implantation for lung volume reduction in COPD patients: results from a German multicenter observational cohort

  • By

  • Eva Pappe

  • Hadis Darvishi

  • Thomas Sgarbossa

  • Jacopo Saccomano

  • Kaid Darwiche

  • Stefan Andreas

  • Stephan Eisenmann

  • Bernd Schmidt

  • Wolfgang Gesierich

  • Nicolas Dickgreber

  • Christian Geltner

  • Joachim Hans Ficker

  • Angelique Holland

  • Björn Schwick

  • Stephan Eggeling

  • Ralf Eberhardt

  • Christian Grah

  • Christoph Hünermann

  • Urte Sommerwerck

  • Andreas Fertl

  • Sylke Kurz

  • Peter Schramm

  • Dinah von Schöning

  • Leif Erik Sander

  • Martin Witzenrath

  • Ralf-Harto Hübner

  • February 13, 2026

  • 0 min

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  • 1

    Endoscopic lung volume reduction (ELVR) with endobronchial valves improves lung function and quality of life in severe COPD patients.

  • 2

    Peri-interventional antibiotic prophylaxis is commonly used during ELVR to prevent complications like pneumonia and acute exacerbations.

  • 3

    Current guidelines do not recommend routine antibiotic use for bronchoscopic procedures due to insufficient evidence of clinical benefit.

  • 4

    The study aims to evaluate the impact of different antibiotic prophylaxis strategies on complications and outcomes in COPD patients undergoing ELVR.

  • 5

    Data were collected from the LE-Registry, focusing on patients treated with one-way valves and assessing various clinical outcomes.

Original Source(s)

Peri-interventional antibiotic prophylaxis in endoscopic valve implantation for lung volume reduction in COPD patients: results from a German multicenter observational cohort

  • by Eva Pappe, Hadis Darvishi, Thomas Sgarbossa, Jacopo Saccomano, Kaid Darwiche, Stefan Andreas, Stephan Eisenmann, Bernd Schmidt, Wolfgang Gesierich, Nicolas Dickgreber, Christian Geltner, Joachim Hans Ficker, Angelique Holland, Björn Schwick, Stephan Eggeling, Ralf Eberhardt, Christian Grah, Christoph Hünermann, Urte Sommerwerck, Andreas Fertl, Sylke Kurz, Peter Schramm, Dinah von Schöning, Leif Erik Sander, Martin Witzenrath, Ralf-Harto Hübner

  • February 13, 2026

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